What is the normal value of jaundice in neonates due to immature liver function

Newborn babies are prone to jaundice, and jaundice is often divided into physiological jaundice and pathological jaundice, so what are the causes of jaundice?

Parents should obviously be familiar with the causes of neonatal jaundice, so what are the causes of neonatal jaundice?

What are the causes of neonatal jaundice

1. Bilirubin is produced

(1) Red blood cell destruction: the fetus is in a low oxygen environment in the mother's womb, and the red blood cells are compensatorily increased, but the life span is short, the blood oxygen content increases after birth, and the excessive red blood cells are quickly destroyed.

(2) High heme oxygenase content: the content is high within 7 days after birth, and the potential for producing bilirubin is high.

2. Immature liver function

(1) Poor ability of liver to take bilirubin: the content of Y and Z proteins in liver cells is insufficient, so that the liver does not take up bilirubin enough.

(2) Poor function of hepatic conjugated bilirubin: the content of glucuronosyltransferase in the liver is low and the activity is insufficient, and the function of conjugated bilirubin is poor.

(3) Poor function of hepatic excretion of bilirubin: the function of excretion of conjugated bilirubin is poor, which is easy to cause cholestasis.

3. Characteristics of entero-liver circulation: the normal flora in the intestine has not yet been established when the newborn is born, and the bilirubin entering the intestine cannot be converted into urobilinogen (fecocobilinogen).

Types and values of neonatal jaundice

1. Physiological jaundice

Usually two days after birth, the newborn can be seen with the naked eye that the skin is a little yellow, reaching a peak in 3~5 days, and disappearing in 7~10 days, at this time, the jaundice index (serum bilirubin value) is generally not more than 15mg/dL is within the normal range.

2. Pathological jaundice

There are many causes of pathological jaundice, followed by full-term childrenprematureThe standards are different, and mothers will be sent to the hospital for observation as long as they find the following conditions:

1. Jaundice is found within 24 hours of birth, which is "early-onset jaundice".

2. The jaundice index rises too high all of a sudden, increasing by more than 5mg/dL a day, which is more common hemolytic jaundice (the blood type of the mother and the baby is incompatible).

3. The jaundice index rises too high, with 15mg/dL.

4. The duration is too long, the general physiological jaundice lasts for 7~10 days, if it is more than two weeks, you should pay attention.