What is the most invasive site of acute leukemia

Acute leukemia is a malignant clonal disease of hematopoietic stem cells. Its cell differentiation is hindered, stagnation in the early stages, apoptosis is inhibited, proliferates and accumulates in the bone marrow and other hematopoietic tissues, and infiltrates other non-hematopoietic tissues and organs.

1. Myeloid cells

1. Granulocytes: can cause fever, infection, etc.;

2. Monocytes: can lead to hepatosplenomegaly and anemia;

3. Red blood cells: can cause anemia, manifested as paleness, fatigue and other symptoms;

4. Megakaryocytes: can cause bleeding tendency, such as skin petechiae, nasal gum bleeding, etc.

2. Lymph nodes

It is commonly found in the lymph nodes of the neck, and can also affect the axillary and groin.

3. Central nervous system

It can cause increased intracranial pressure, headache, vomiting, papilledema and other symptoms; It can also cause positive meningeal irritation, manifested as nuchal rigidity, Klinefelter sign, etc.

Fourth, the digestive system

It can cause symptoms such as nausea, vomiting, diarrhea, and blood in the stool.

5. Genitourinary system

It can cause symptoms such as proteinuria, hematuria, oliguria, and even anuria.

6. Bones

It can cause bone pain, fractures and other symptoms.

7. Blood system

It can cause coagulation dysfunction, manifested as purpura, ecchymosis, petechiae, etc.

8. Other parts

In addition to the above, it may also affect the heart muscle, lungs, fundus and other parts.

It is recommended that patients seek medical treatment in a timely manner, and targeted therapy can be carried out with drugs such as imatinib mesylate tablets and nilotinib capsules under the guidance of doctors. If necessary, it can also be treated with allogeneic hematopoietic stem cell transplantation.