What is cholecystitis?

We may all know that the incidence of cholecystitis is particularly large, and many people are prone to cholecystitis disease, when cholecystitis attacks, the patient will die of pain, everyone only knows that this is a physical disease, but do not know what disease it belongs to, so what kind of disease is cholecystitis? Let's find out.

What is cholecystitis?

Acute cholecystitis is caused by abrupt obstruction or incarcerated cystic duct obstruction of gallstones in the gallbladder, and cystic duct torsion, stricture, and obstruction of biliary roundworms or biliary tumors can also cause acute cholecystitis. In addition, in the process of aging, the gallbladder wall gradually becomes hypertrophied or atrophied, and the contractile function decreases, resulting in cholestasis, concentration and the formation of cholates; The end of the common bile duct and the ODDI sphincter become relaxed, and retrograde infection is susceptible; Systemic atherosclerosis, increased blood viscosity can exacerbate gallbladder artery ischemia.

After obstruction of the cystic duct or gallbladder neck, stagnant bile in the gallbladder concentrates to form cholates, which irritate the gallbladder mucosa and cause chemical cholecystitis (early); At the same time, bile retention makes the pressure in the gallbladder continue to increase, the swollen gallbladder first affects the venous and lymphatic reflux of the gallbladder wall, the gallbladder appears congested and edema, when the gallbladder pressure is 5.39KpA (55CMH2O), the arterial blood flow in the gallbladder wall is blocked, the gallbladder is ischemic injury, the ischemic gallbladder is prone to secondary bacterial infection, aggravating the process of cholecystitis, and finally complicated by gallbladder gangrene or perforation.

If the cystic duct is obstructed without circulatory disorders and bacterial infections of the gallbladder wall, a gallbladder effusion develops. Recent studies have shown that phospholipase A can be released from the damaged gallbladder mucosal epithelium due to cholestasis or stone incarceration, and the lecithin in the bile is hydrolyzed into lysolecithin, which in turn changes the integrity of mucosal epithelial cells and causes acute cholecystitis.

What kind of disease is cholecystitis, do you have your own understanding? It is hoped that patients with cholecystitis will carefully understand their own diseases and do a good job of examination and treatment, and when they have signs of cholecystitis, they should go to a professional hospital for examination, so as not to lead to the aggravation of cholecystitis or the misdiagnosis and mistreatment of cholecystitis, which threatens the health of patients.