What happens if there is no obvious change in 6 months of taking medicine for tuberculosis? What to do?

The lack of significant change in pulmonary tuberculosis medicine for 6 months may be caused by factors such as non-standard medication, drug-resistant tuberculosis, autoimmunity, diabetes, AIDS, etc., and the condition can be improved through general treatment, drug treatment, and surgical treatment.

1. Non-standard medication: pulmonary tuberculosis is mainly a disease caused by Mycobacterium tuberculosis infection, usually after the disease, it is necessary to use anti-tuberculosis drugs to treat the condition, if the correct medication is not followed by the doctor's instructions during the medication, it can lead to poor anti-tuberculosis treatment effect, causing no obvious change for 6 months. In this case, it is necessary to change the medication method and follow the doctor's instructions to use the medication on time and in the right amount.

2. Drug-resistant tuberculosis: If the patient is infected with drug-resistant Mycobacterium tuberculosis, the use of general anti-tuberculosis drugs for related diseases will not have obvious effects, and patients can also have related conditions. For this condition, it is necessary to perform a drug susceptibility test on the patient, and then select a sensitive anti-tuberculosis drug to treat the condition, such as moxifloxacin hydrochloride tablets, clofazimine soft capsules, etc.

3. Autoimmunity: If the patient has autoimmunity, it can lead to immune disorders, and the immune system cannot suppress the pathogen while undergoing anti-tuberculosis treatment, so there can be no obvious changes. For autoimmunity, further immunosuppressants are needed for treatment, and commonly used drugs are cyclosporine capsules, methotrexate tablets, etc.

4. Diabetes: If the patient has diabetes, the incidence of infection can be increased due to the continuous increase in blood sugar, resulting in a decrease in immunity, which can cause the patient to take medicine for 6 months and the improvement effect is not good. For diabetes, hypoglycemic drugs need to be used to treat the condition, such as metformin hydrochloride sustained-release tablets, glimepiride tablets, etc.

5. AIDS: If the patient has pulmonary tuberculosis combined with AIDS, the immune function can be impaired due to the related diseases, and the continuous decline of immunity can also affect the effect of anti-tuberculosis treatment and cause related manifestations. For AIDS, antiretroviral drugs need to be used to treat the condition, such as abacavir bivudine tablets, lamivudine tablets, etc.

Tuberculosis patients also need to improve their living habits, adjust their diet, improve their immunity, and promote the treatment and recovery of the disease.