What causes stomach ulcers?

Many people are more curious about the disease of gastric ulcer, because gastric ulcer is a common disease in life, and many people are very prone to gastric ulcers, but most patients do not know what the cause of gastric ulcers is.So what causes stomach ulcers?how are stomach ulcers caused?what causes stomach ulcers?

1. Helicobacter pylori infection

Helicobacter pylori can produce a large number of harmful substances, thereby causing damage to the gastric mucosa and gastric mucosal barrier, so Helicobacter pylori is the main cause of chronic gastritis in the human body, and has a direct relationship with gastric ulcer and duodenal ulcer.

2. Drug factors

In the treatment of chronic diseases such as cardiovascular and cerebrovascular diseases, commonly used drugs such as aspirin, indomethacin, and reserpine can cause direct or indirect damage to the gastric mucosa after taking them, and the incidence of gastric ulcers in long-term low-dose aspirin patients is 5 times that of those who do not take it.

3. Smoking factor

The nicotine in tobacco can directly damage the gastric mucosa, and smoking can also cause intestinal fluid reflux and inhibit the synthesis of prostaglandins, thereby promoting the occurrence of ulcers caused by damage to the gastric mucosa. In addition, smoking can also increase the incidence of ulcer complications, affect the healing of ulcer surface and easily promote ulcer recurrence.

4. Dietary factors

Diet and the onset of ulcer disease are not well understood, but alcohol, coffee, strong tea, cola and other beverages can stimulate increased gastric acid secretion, and long-term consumption of large amounts may increase the risk of ulcers.

5. Mental factors

People with long-term stress, anxiety or mood swings are prone to ulcer disease, and patients who have healed ulcers are prone to recurrence or complications when they have mood swings.

6. Disease factors

Bile reflux can cause damage to the gastric mucosal barrier and various chronic diseases of the liver, kidney, heart, lungs and other organs can lead to the weakening of the mucosal barrier and lead to the occurrence of ulcers.

7. Genetic factors

Patients with gastric ulcers often have a family history of the disease, and the incidence of gastric ulcers in the families of patients with gastric ulcers is 3 times higher than in the general population.

8. Causes of recurrent gastric ulcers

1. The characteristics of the disease itself

Patients with a history of gastric ulcers are prone to recurrence because the scarring of the ulcer surface leads to fibrosis of the muscularis propria, which can cause gastric deformation and affect the motor function of the stomach. Generally, the recurrence of gastric ulcers in the same or proximal location of the lungs is present. These results indicate that the recurrence of ulcers is closely related to the location of the scar formed by the original ulcer.

2. Smoking

Smoking can increase the recurrence rate of gastric ulcers because the nicotine in tobacco can directly damage the gastric mucosa. Smoking can also cause intestinal fluid reflux, inhibit the synthesis of prostaglandins, thereby promoting damage to the gastric mucosa, resulting in the recurrence of gastric ulcer disease, and the recurrence rate of gastric ulcer in long-term smokers is about 75%.

3. Helicobacter pylori infection

Helicobacter pylori is not only closely related to the onset of ulcers, but also is likely to be an important factor in ulcer recurrence, and the recurrence rate of gastric ulcers can be significantly reduced after the H. pylori is killed during treatment.

4. Dietary factors

Irregular life, gastric and duodenal ulcer after healing do not pay attention to the rules of life and diet, such as too hungry, too full, eating irritating, acidic, too hot, too cold and rough food, will produce adverse stimulation to the gastric mucosa and ulcer surface and induce the recurrence of gastric ulcer.

5. Mental factors

A survey of people under the age of 60 with recurrent gastric ulcers found that 50% of the population was related to mental stress. Emotions affect physical and physiological changes, because the adverse stimulation of the cerebral cortex, mental tension, mood swings, etc., will affect the digestive function of the stomach and the healing of the ulcer surface, therefore, mental stress can induce the recurrence of gastric ulcers.

6. Other factors

1. Age: Young and middle-aged people are prone to recurrence, and those under the age of 50 have the greatest risk of recurrence after the ulcer is cured.

2. Family history: The recurrence rate of patients with a family history of gastric ulcer disease is about 80%, which is significantly higher than that of patients without a family history (44.8%).

7. Tips

The above factors indicate that the recurrence of gastric ulcer is related to a variety of factors, but for a certain patient, it may be one of the factors that can cause the recurrence, or it may be the result of the interaction of several factors that promote the recurrence of gastric ulcer.