What are the main drug treatments for vitiligo?

Vitiligo is a common acquired depigmentation disorder that can occur in various parts of the body. The cause is unknown, but it may be related to genetics, autoimmunity, and other factors. Clinically, the treatment of vitiligo is mainly through topical drugs and oral drugs to improve symptoms.

1. Topical drugs

1. Glucocorticoids: such as mometasone furoate cream, halomethasone cream, etc., can inhibit local inflammatory response, reduce the number of T lymphocytes, thereby promoting melanin production;

2. Calcineurin inhibitors: such as tacrolimus ointment, pimecrolimus cream, etc., can regulate immune system function, stimulate melanin synthesis, and have no obvious irritating effect on the skin;

3. Vitamin D derivatives: such as calcipotriene ointment, tacalacisole ointment, etc., which have anti-inflammatory, immune-regulating effects, and help restore the normal pigment metabolism process;

4. Photosensitizers: such as psoralen tincture, etc., can be used under the guidance of a doctor, suitable for patients with stable localized vitiligo, which can make the affected area produce more melanocytes and increase the melanin content, and then make the vitiligo subside.

2. Oral medications

Commonly used drugs include prednisone tablets, dexamethasone acetate tablets, methotrexate tablets, etc., which can achieve the purpose of adjuvant therapy by affecting the function of melanocytes in the human body or inhibiting melanocyte apoptosis.

It can also be used according to the doctor's instructions to apply traditional Chinese medicine for conditioning, and commonly used Chinese medicine prescriptions include Taohong Qingxue Soup, Baidai Pill, etc., which can also play a certain role in curative effect. If the above methods do not work well, it is recommended to go to the hospital in time and choose a suitable regimen for treatment under the guidance of a doctor.