What are the causes of high blood sugar in newborns
Not only adults will have hyperglycemia, but also newborns, what causes neonatal hyperglycemia? I believe that every newborn patient's parents must be very eager to know the answer, today we will take a closer look at the causes of neonatal hyperglycemia.
1. Stress is a common cause of neonatal hyperglycemia.
2. Immature blood sugar regulation function: neonates with poor glucose tolerance, especiallyprematureand children with SGA, lacking the Staub-Trugot effect (i.e., decreasing blood glucose levels and accelerated rate of glucose disappearance after repeated glucose infusions) in adults, which is associated with imperfect pancreatic B cell function, insensitive response to glucose infusion, and poor insulin activity. Small gestational age, low body weight, and younger days are more pronounced. Sugar tolerance is lowest on the first day of life. Patients with a body weight of >1kg cannot even tolerate the glucose infusion rate of 5~6mg/(kg·min).
3. Others:
Iatrogenic hyperglycemia is often due to:prematureand very low birth weight infants with a rapid rate of glucose infusion, or when total intravenous nutrition is not caused by the inability of exogenous glucose infusion to inhibit endogenous glucose production. motherparturitionShort-term use of glucose and glucocorticoids; The use of hypertonic glucose, epinephrine, and long-term glucocorticoids during resuscitation in the delivery room has an effect on blood glucose levels; Treatment with aminophylline during apnea activates hepatic glycogenolysis and inhibits glycogen synthesis.
Pathophysiology
Asphyxia, cold, or sepsis can cause changes in catecholamines, cortisol, acid-base status, etc., while glucagon, gluconeogenesis, and insulin response changes can lead to hyperglycemia, and endotoxic qualities can also directly affect insulin response and cause hyperglycemia.It is mostly transient.
The above is an introduction to the causes of high blood sugar in our newborns, I believe that parents also have some understanding, I hope that every parent can start from the small things in life, take care of their children, so that they have a healthy body, a happy childhood.