What are the causes of cholecystitis?

Chronic cholecystitis is the most common disease in life, this is a very serious disease, in the treatment, we must grasp the cause of its onset, find the cause of the disease, in the treatment will be of great help, are the way to check it, we are not particularly understanding, the detailed cause of the cause of our look at the following description.

(1) The cause of the disease

1. Chronic calculous cholecystitis is the same as acute cholecystitis, because gallstones cause repeated small attacks of acute cholecystitis, that is, chronic cholecystitis and acute cholecystitis are manifestations of different stages of the same disease.

2. Chronic acalculous cholecystitis accounts for 2%~10% of all patients with gallbladder lesions at the time of autopsy or surgery.

3. Chronic atrophic cholecystitis with stones, also known as porcelain bottle-like gallbladder. Inflammation and irritation caused by stones lead to calcification of the gallbladder wall, which can be confined to the mucosa, muscle, or both. It is more common in women over 65 years of age.

4. Yellow granulomatous cholecystitis is relatively rare, accounting for about 0.7%~1.8% of gallbladder inflammatory diseases. It is caused by an inflammatory reaction caused by the entry of bile lipids into the connective tissue of the gallbladder lumen.

(2) Pathogenesis

1. Chronic calculous cholecystitisChronic cholecystitis thickens the gallbladder wall due to connective tissue hyperplasia and tissue edema, lymphocyte infiltration between the whole layer, and the gallbladder contains mucinous substances, and sediment, gallbladder or stones can be seen; In severe cases, the muscle layer is replaced by fibrous tissue, the gallbladder wall is scarred, and the cystic duct is obstructed by a fibrous mass. Bacterial cultures of bile are often negative.

2. Chronic acalculous cholecystitis

(1) Metabolic disorders: due to the disorder of cholesterol metabolism, cholesteryl esters are deposited in the mucosa of the gallbladder and cause mild inflammation, and about half of them can form cholesterol stones. The appearance of the gallbladder is mostly unobvious, and the cyst wall may be slightly thickened and slightly pale; The gallbladder mucosa is obviously congested and hypertrophied, and there are countless yellow-white cholesteryl ester precipitates on the mucosa, which are shaped like strawberries, so this disease is also called "strawberry gallbladder".

(2) Infection: bacteria can come from the intestine and biliary tract and go up to the gallbladder; In sepsis, bacteria can reach the gallbladder through the bloodstream or lymphatic routes. About one-third of patients have bacterial growth in bile cultures. Chronic cholecystitis can also be caused by a viral infection, and about 15% of patients have a history of hepatitis. Fungal and parasitic infections can also lead to chronic cholecystitis.

What are the causes of cholecystitis? In life, we must have a healthy future with serious examination and treatment, try not to let cholecystitis affect our health, timely detection, disease can restore health in time, pay attention to our own health in life, so as not to bring serious injury, I hope we don't have too much pressure, as long as we work hard to do treatment, I believe that the disease will recover.