Treatment of Mycoplasma pneumoniae

There are many ways to treat the disease, before the treatment of the disease, you need to understand the disease, so that when the disease is treated, you will know how to treat it, and when the disease is treated, the patient should also actively cooperate, and the treatment will not help the disease to improve.

Treatment for Mycoplasma pneumoniae:

Treatment of patients with mycoplasma pneumonia

Mycoplasma pneumonia is mainly treated with antimicrobials. Because cough is the most prominent clinical manifestation of mycoplasma pneumonia, low-dose antitussives and expectorants may be given appropriately. Patients with severe disease and hypoxia should be given oxygen in time. For severe wheezing, bronchodilators may be used. Adrenocorticosteroids can be used in patients with rapidly progressing mycoplasma pneumonia or pulmonary disease with atelectasis, pulmonary interstitial fibrosis, bronchiectasis, or extrapulmonary complications due to rapid progression of the disease in the acute phase.

Treatment of Mycoplasma pneumoniae infection in children

For mild Mycoplasma pneumoniae infection, drugs can be taken by mouth, including erythromycin and newer macrolides such as azithromycin, clarithromycin, and roxithromycin.

The 2005 edition of the Pharmacopoeia of the People's Republic of China clearly states that the efficacy and safety of azithromycin have not been established in children with CAp for &6 months, and should be used with caution. Intravenous azithromycin has the potential to cause anaphylaxis shock. Severe Mp infection can be treated intravenously during the acute phase of the disease, but it should still be switched to gastrointestinal medication and sequential therapy should be used in a timely manner.Intravenous drops of erythromycin and azithromycin have adverse reactions such as gastrointestinal discomfort, and there are clinical practices in pediatrics to add vitamin B6, vitamin K1, sodium bicarbonate, 654-2 and other drugs, but there is no evidence to support the effectiveness of this empirical drug, and the addition of drugs may change the blood pH value, affecting the efficacy of erythromycin and azithromycin, and the activity of these drugs is enhanced under alkaline conditions.

The duration of mycoplasma infection varies depending on the site of the lesion, and mild upper respiratory tract infections usually range from L0 to 14 days. It should be noted that some children may continue to present mycoplasma in respiratory secretions for several months after treatment, resulting in recurrence and dissemination. The recommended course of treatment for mycoplasma pneumonia is 2-3 wk for mild cases, 4 wk for severe cases, and it will be longer for some cases, which should depend on the specific condition.

Medications and their dosages are available

The minimum inhibitory mass concentration of erythromycin:mycoplasma was 0.0156 tzg/mL, and the ratio of intracellular to extracellular levels was 6.6:1. 30-50mg/(kgd) for children, divided into 3~4 oral doses. Intravenous infusion can also be used, and patients with Mpemia are the strongest indication for intravenous erythromycin.

Roxithromycin: 5~10mg/(kgd) for children, divided into 2 oral doses.

Azithromycin: 10mg/(kgd) for children, once orally, the effective tissue level can be maintained for 7 days after oral administration for 3 days, so it is discontinued for 4 days as a course of treatment.The usual regimen used abroad is: 10mg/kg on the first day, 5mg/kg on the 2nd ~ 5th day, and the total dose is still 30mg/kg. Clinical overuse of intravenous azithromycin should be corrected. Patients with severe Mp pneumonia and pleurisy can be treated intravenously in the acute phase of the disease, but sequential therapy should also be used and promptly converted to transVI administration.

Clarithromycin: the dosage is l0~15mg/(kgd), divided into 2 oral doses. Spiramycin, crosssamycin, etc., have been less commonly used in pediatrics.

After understanding the treatment methods of Mycoplasma pneumoniae, the above methods can be selected when treating Mycoplasma pneumoniae, but when treating Mycoplasma pneumoniae, patients should pay attention to this time, and some bad lifestyle habits should be improved, otherwise it will have a great impact on the treatment of the disease.