Patients with gout are susceptible to diabetes mellitus, and comprehensive treatment should be initiated from these methods

Diabetes mellitus and gout are both diseases caused by metabolic abnormalities in the body, and both have a common pathogenesis, and overnutrition is one of the pathogenic factors, and the pathogenesis can be caused by insulin resistance. Therefore, people with superior dietary conditions are susceptible to this disease. Obesity, gout, and diabetes are thought to be triadics, and obesity can induce hyperuricemia and hyperglycemia.

People with gout are susceptible to diabetes

According to a recent report on the website of the National Center for Biotechnology Information, researchers at Brigham and Women's Hospital in the United States found that gout patients, especially women, have a higher risk of diabetes.

The researchers obtained a database of people with diabetes from a variety of sources, including more than 13 million blood test results and pharmacy dispensing records, including 10 years of patient data from 2003 to 2012. The researchers divided the patients into three groups: gout patients, osteoarthritis patients and patients without gout, and after analyzing the data of 54,000 gout patients and 16,000 osteoarthritis patients, it was found that the proportion of gout patients with diabetes was higher, and the proportion of female patients was much higher. Compared to the normal group, people with gout had 3 times the risk of developing diabetes compared to those without gout. Therefore, the researchers believe that female gout patients should be screened for blood sugar frequently.

Comprehensive treatment of gout and diabetes

Uric acid in the human body is produced by the metabolism of purines (intermediate metabolites of proteins) in food and by the body's own metabolism. Therefore, if the blood sugar level is high, the uric acid value will also be higher. According to incomplete statistics, about 0, 1%~9% of diabetic patients with gout, and 2%~50% of patients with hyperuricemia. Elevated blood uric acid levels in people with diabetes may be caused by:

1. The xanthine conversion into uric acid increases in diabetic patients.

Patients with type 2 and type 2 diabetes mellitus are often accompanied by decreased renal blood flow, which causes glomerular hypoxia, increased lactate production, and competitive excretion with uric acid, resulting in decreased uric acid excretion.

3. Hyperinsulinemia: insulin can promote the reabsorption of uric acid by the kidneys, resulting in an increase in blood uric acid.

Generally, comprehensive treatment is carried out from five aspects: dietary therapy, drug therapy, exercise therapy, education and psychological therapy, and disease monitoring, with dietary therapy being the most important.

1. Control the total daily dietary calories, which is the general principle of dietary therapy, and other measures should not be contrary to this. Limit refined sugars and eat more fresh vegetables and fruits that are low in sugar to provide adequate supply of inorganic salts and vitamins. Limit the intake of protein, fat and cholesterol, choose foods with less purines such as milk and eggs as protein sources, eat less seafood, animal offal, fatty meat, light food, and use less condiments. Strictly prohibit alcohol, drink more water, at least 2500~3000 ml per day.

2. When the patient goes to a regular hospital, ask a specialist doctor to formulate a medication plan, and do not believe in the so-called "radical cure" and "miraculous effect", because with the current medical level, there is no cure for these two diseases.

3. It is very important to adhere to physical exercise that suits you and control your ideal weight, because obesity can induce hyperglycemia and hyperuricemia.

4. Encourage patients to establish confidence in overcoming diseases from the perspectives of medical treatment and family members, so that they can learn relevant medical knowledge and simple psychological counseling methods. Supplementing diet with medication and perseverance is beneficial in controlling the development of the disease, greatly reducing various complications, and indirectly playing a positive therapeutic role in patients.

In short, diabetes and gout are preventable and treatable, and complications of multiple organs will occur if not prevented or treated, and delaying and stopping the development and deterioration of the disease and complications can reduce the mortality rate of disability and improve the quality of life of patients.