Mycoplasma pneumoniae infection is not contagious for several days after prognosis
Mycoplasma pneumoniae is a microorganism that can live independently between bacteria and viruses, with a size of 200 nm. The cell membrane, which has no cell wall and consists of only 3 membranes, is often confused with the L-type of bacteria, and the colonies of the two are similar, and can grow and divide on a cell-free medium, containing RNA and DNA, which are metabolized to produce energy and are sensitive to antibiotics.
Mycoplasma is the causative organism of a variety of animal diseases, and 8 types have been found so far, among which only Mycoplasma pneumoniae is definitely pathogenic to humans, mainly respiratory diseases.
Resistant to thallium acetate, penicillin, etc.
It is caused by airborne secretions from the mouth and nose, causing sporadic and small prevalent respiratory infections, mainly in children and adolescents, and is now found in adults, and is more common in autumn and winter. Mycoplasma pneumoniae can be found in respiratory secretions 2~3 days before the onset of the disease until several weeks after recovery.
It is infected by contact, grows between the ciliated epithelium, does not invade the lung parenchyma, and has neuraminic acid receptors on the cell membrane, which can adsorb to the surface of the host's respiratory epithelial cells, inhibit ciliary activity and destroy epithelial cells, and produce hydrogen peroxide at the same time, further causing local tissue damage.
Its pathogenicity may be related to the patient's allergic reaction to the pathogen or its metabolites. Humoral immunity is caused by infection, and antibodies are present in the serum of most adults, so the disease is rare.
Treatment with erythromycin, crosssamycin, and tetracyclines is effective and shortens the duration of the disease. erythromycin 0.5 g every 8 hours; The gastrointestinal reaction of crosssamycin is mild, and the effect is similar to that of erythromycin, and the dosage is 1.2~1.8g/d, divided orally; Tetracycline 0.5 g every 6 hours.
Treatment should be continued for 2~3 weeks to avoid recurrence