I want to know what the common causes of vitiligo are

vitiligoIt is a common acquired depigmentation disorder, and its cause is unknown. At present, it is believed that the occurrence of this disease may be related to genetics and autoimmune factors.

1. Heredity:vitiligoIt has a certain tendency to familial aggregation, and about 30% of patients have a positive family history, indicating that the disease has a certain genetic predisposition;

2. Autoimmune factors: Some studies have shown that in people with vitiligo, a variety of cytokines and inflammatory mediators can be detected to be involved in the process of melanocyte damage, and these inflammatory substances can inhibit the function of T lymphocytes, resulting in melanocyte destruction and vitiligo formation; Some studies have also found that serum anti-thyroglobulin antibody (TGA) levels are markedly elevated in patients with vitiligo, suggesting possible autoimmune abnormalities;

3. Neurochemical factors: Studies in recent years have shown that mental stress or depressive states may induce vitiligo, because the dysfunction of the sympathetic nervous system will lead to a series of stress responses in the body, such as increased secretion of adrenal corticosteroids, which in turn affects the process of melanin metabolism and eventually triggers vitiligo.

4. Other reasons: ultraviolet radiation is inducedvitiligoAn important factor, especially long-term exposure to sunlight, promotes melanin synthesis in the skin and reduces tyrosinase activity, thereby hindering the normal synthesis of melanin.In addition, trauma may cause localizationvitiligokind of change.

If you suspect that you have vitiligo, please consult a professional doctor for diagnosis and treatment. At the same time, it is necessary to avoid sun exposure and traumatic stimulation, and maintain a good attitude and eating habits will also help the recovery of the disease.