Does jaundice caused by hemolysis cause fever

Jaundice: The bilirubin decomposed by the destruction of red blood cells is yellow, it can be distributed throughout the body, making the color of the body's tissues yellow, because the skin and sclera (commonly known as white eyeballs) are located on the surface of the body, the yellowing is the most obvious, that is, jaundice.Most newborns will have jaundice after birth, but when jaundice develops too early, develops too quickly, or when blood bilirubin levels are too high, hemolysis is a concern. Jaundice in infants with hemolysis usually develops within 24 hours or 2 days after birth.

Bilirubin encephalopathy: High levels of bilirubin in the blood can damage brain cells, causing bilirubin encephalopathy, which is the most serious comorbidity of hemolytic disease. Generally occurs in:parturitionAfter 2~7 days, jaundice aggravated, and the child developed neurological symptoms, such as drowsiness, feeding difficulties, binocular gaze, convulsions, etc. If not treated in time, it can cause death or sequelae such as motor dysfunction and mental retardation.

Anemia: Babies with hemolysis have anemia that varies from mild to severe due to the destruction of red blood cells.

Hepatosplenomegaly: In severe hemolysis, hydrops fetalis occurs and there may be significant hepatosplenomegaly, which is more common in Rh hemolytic disease.

Fever: fever may be a reaction to hemolysis in children or in more severe cases of bilirubin encephalopathy. The fever may not necessarily be very high, but if it is due to the latter, it means that the disease is more serious.

Pediatric jaundice, ABO, blood group incompatibility, hemolytic disease

It usually occurs in the mother's blood group O and the father's blood group A, B, and AB. The blood type of the fetus is determined by a combination of genes passed on from each parent, so the blood type of the fetus may be different from that of the mother.

For example, if the mother of type O blood is pregnant with a fetus with type A blood inherited from the father, because there is no A antigen in the mother of type O blood, when the red blood cells of type A fetal enter the mother's body, the mother will produce anti-A antibodies, and the anti-A antibody will cause the baby's red blood cells to destroy and dissolve the blood when they enter the baby's body.

However, not all babies born to mothers with type O blood will develop hemolytic disease, but some babies will develop hemolytic disease, some babies will not have disease, some have mild symptoms, and some have severe symptoms. This is related to the amount of antibodies in the mother, the degree to which the antibodies bind to fetal red blood cells, the strength of A(B) antigens, and the compensatory hematopoietic capacity of the fetus.

Because of the presence of substances similar to the A(B) antigen in nature, the mother with blood group O is often exposed to it before pregnancy, and then these similar blood group antigen substances can stimulate the mother with blood group O to produce A(B) antibodies and become the motherpregnantLater, this antibody can enter the fetus through the placenta and cause hemolysis.