Causes of high neonatal jaundice

1. Newborns have too many red blood cells in the body, and too much bilirubin is produced after the red blood cells are destroyed, and bilirubin is the direct cause of jaundice, so newborns will have high jaundice.

2. The metabolism of bilirubin requires the participation of liver enzymes in the liver, and the liver function of newborns is not very perfect, so it leads to insufficient secretion of liver enzymes, which makes bilirubin excreted untimely, resulting in high jaundice.

3. The discharge of bilirubin requires the participation of the biliary tract, and the biliary function of newborns is not perfect, so the accumulation of bilirubin in the body cannot be discharged in time, resulting in high bilirubin and high jaundice.

4. Bilirubin can also be excreted from the stool, but the neonatal meconium is relatively viscous, resulting in the discharge of bilirubin is not very smooth, which makes the bilirubin in the newborn too high, resulting in high jaundice.

5. In addition, the incompatibility of mother and child blood group will also lead to the accumulation of bilirubin in the body of the newborn and cannot be discharged, and the pathological jaundice may be caused by neonatal diseases, such as neonatal asphyxia, premature birth, infection and other factors, which can lead to high neonatal jaundice.

6. Breastfeeding can also lead to the accumulation of bilirubin in the newborn's body, resulting in high jaundice in the newborn.

Pediatric jaundice: The dangers of high neonatal jaundice

Physiological jaundice in newborns can resolve on its own, but pathological jaundice is a group of diseases composed of many causes that must be detected and treated as early as possible. Newborns with severe jaundice should be alert to the occurrence of kernicterus, especially immature infants, the younger the age of the month, the higher the incidence, generally within 12-48 hours after the occurrence of severe jaundice, lethargy, weakness in sucking, hypotonia, vomiting, lack of milk and other symptoms, at this time, if treated in time, can be fully recovered.

Physiological jaundice of neonates: In the past, it was thought that treatment was not necessary, but in view of the current promotion of eugenics and the improvement of population quality, special attention should be paid to the following points:

1. Start milk early in advance to accelerate the discharge of meconium.

2. Starvation, hypoxia, constipation, dehydration, acidosis, cranial hematoma, etc. can aggravate physiological jaundice and should be treated.

Hyperintercholisemia: the harm is mainly to produce kernicterus, the study of kernicterus, in the past, it was believed that indirect bilirubin is fat-soluble and lipophilic, which is a free state, and has an affinity with brain cells rich in cerebral phospholipids, and is easy to damage the nerve nucleus through the blood-brain barrier and cause kernicterus.

Pathological jaundice, regardless of the cause, can cause "kernicterus" in severe cases, and its prognosis is poor, in addition to causing nervous system damage, severe can cause death.Therefore, the prevention of pathological jaundice in newborns should be emphasized, such as preventing infection of toxoplasma gondii and rubella virus during pregnancy, especially in the first trimester; prevent the onset of sepsis after birth; Newborns are vaccinated against hepatitis B at birth, etc.