A little bit of knowledge about Mycoplasma genitalium infection
Reproductivetract infection (RTI) is an infection caused by microorganisms normally present in the reproductive tract or external microorganisms entering the reproductive tract during medical procedures or sexual contact, and mycoplasma infection is a common sexually transmitted infection in women, and it is also a difficult problem in clinical management.
Now mycoplasma and chlamydiavaginitisThe therapeutic aspects are summarized below.
1. Pathogens
Pathogens of mycoplasma infection include Mycoplasma hominisis (MH), Ureaplasma urealyticum (UU), and Mycoplasma genitalium (MG). Among them, ureaplasma ureaplasma has the highest infection rate, which can not only cause inflammation of the urinary tract and genital tract, such as non-gonococcal urethritis,vaginitis，Cervicitis, endometritis, pelvic inflammatory disease, severe cases can cause infection in pregnant women, infertility,Fetal intrauterine growth retardation, and the recurrence rate is high, making treatment difficult.
2. Mode of transmission
Mycoplasma is found in the vagina, around the urethral opening, outside the cervix, and in the urine and is mainly transmitted through sexual contact. When infected in pregnant women, it can spread vertically through the placenta. During childbirth, the fetus can also be infected through a contaminated birth canal.
3. Clinical manifestations
In women, the site of infection is usually in the cervix and then invades the vagina to cause mycoplasmavaginitis。 mycoplasmavaginitisInflammation of the reproductive system that spreads around the cervix is common. Most of them have no obvious symptoms, and a small number of severe patients have a feeling of vaginal slumping, and when the infection spreads to the urethra, frequent urination and urgency are the main symptoms that attract the attention of patients.
When the infection is localized to the cervix, it manifests as increased vaginal discharge, opacity, cervical edema, hyperemia, or superficial erosions.Infection spreads to the urethra and manifests as flushing, congestion, and squeezing of the urethral meatus, with a small amount of discharge and rarely tenderness. The most common comorbidity of mycoplasma infection is salpingitis, and a small number of patients may present with endometritis and pelvic inflammatory disease.
4. Diagnosis
Mycoplasma culture: use a sterile cotton ball to remove vaginal and cervical secretions, insert a sterile cotton swab into the cervix 1~2cm, and gently rotate to remove the secretions containing columnar epithelial cells.
5. Treatment
Due to the lack of cell wall in mycoplasma, antimicrobial drugs that inhibit cell wall synthesis by β-lactams are ineffective, and mycoplasma infections tend to have a slow and long curative effect, so the correct choice of drugs is crucial for whether it can be cured.
Generally speaking, the susceptibility rate of crosssamycin, doxycycline and memanmycin to mycoplasma is more than 90%, and it is the main antibiotic for the treatment of mycoplasma.Antibiotics may be selected based on susceptibility testing if necessary.
6. Mycoplasma infection in pregnancy
The first treatment is azithromycin 1 g orally and erythromycin 0.5 g/day orally for 14 days.
The husband should also be treated at the same time as the treatment, and condoms should be used during the treatment.